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P Simon Jones

P Simon Jones

Research Associate


Office Phone: (7)60697

Departments and Institutes

Clinical Neurosciences:

Research Interests

Imaging analysis and study design in Professor James Rowe's SyReN Group. Mainly looking at impulsivity and control in Parkinson's disease, dementia and drug addictioin using structutral MR, PET and fMRI.

Keywords

  • Frontotemporal dementia
  • cognitive
  • behaviour
  • neuroscience
  • dementia
  • Parkinson's disease

Key Publications

2015

Jones, P. S., Pomeroy, V. M., Wang, J., Schlaug, G., Tulasi Marrapu, S., Geva, S., . . . SWIFT-Cast investigators. (2015). “Does stroke location predict walk speed response to gait rehabilitation?.” Hum Brain Mapp. doi:10.1002/hbm.23059

Mikkelsen, I. K., Jones, P. S., Ribe, L. R., Alawneh, J., Puig, J., Bekke, S. L., . . . Mouridsen, K. (2015). “Biased visualization of hypoperfused tissue by computed tomography due to short imaging duration: improved classification by image down-sampling and vascular models.” European Radiology, 25(7), 2080-2088. doi:10.1007/s00330-015-3602-x

Ersche, K. D., Hagan, C. C., Smith, D. G., Jones, P. S., Calder, A. J., & Williams, G. B. (2015). “In the face of threat: neural and endocrine correlates of impaired facial emotion recognition in cocaine dependence.” Transl Psychiatry, 5, e570. doi:10.1038/tp.2015.58

Agarwal, S., Matys, T., Marrapu, S. T., Scoffings, D. J., Mitchell, J., Jones, P. S., . . . Warburton, E. A. (2015). “Is CT-Based Perfusion and Collateral Imaging Sensitive to Time Since Stroke Onset?.” Front Neurol, 6, 70. doi:10.3389/fneur.2015.00070

Smith, D. G., Jones, P. S., Williams, G. B., Bullmore, E. T., Robbins, T. W., & Ersche, K. D. (2015). “Overlapping decline in orbitofrontal gray matter volume related to cocaine use and body mass index.” Addiction Biology, 20(1), 194-196. doi:10.1111/adb.12081

2014

Ersche KD, Hagan CC, Smith DG, Abbott S, Jones PS, Apergis-Schoute AM, Döffinger R (2014), “Aberrant disgust responses and immune reactivity in cocaine-dependent men.” Biol Psychiatry 75(2):140-7 Details

Patel AX, Kundu P, Rubinov M, Jones PS, Vértes PE, Ersche KD, Suckling J, Bullmore ET (2014), “A wavelet method for modeling and despiking motion artifacts from resting-state fMRI time series.” Neuroimage 95:287-304 Details

Alawneh, J. A., Moustafa, R. R., Marrapu, S. T., Jensen-Kondering, U., Morris, R. S., Jones, P. S., . . . Baron, J. C. (2014). “Diffusion and perfusion correlates of the 18F-MISO PET lesion in acute stroke: pilot study.. Eur J Nucl Med Mol Imaging, 41(4), 736-744”. doi:10.1007/s00259-013-2581-x

2013

Agarwal S, Scoffings DJ, Jones PS, Marrapu ST, Barry PJ, O'Brien EW, Baron JC, Warburton EA (2013), “Interaction of age with the ischaemic penumbra, leptomeningeal collateral circulation and haemodynamic variables in acute stroke: a pilot study.” J Neurol Neurosurg Psychiatry 84(3):271-6 Details

Alawneh JA, Moustafa RR, Marrapu ST, Jensen-Kondering U, Morris RS, Jones PS, Aigbirhio FI, Fryer TD, Carpenter TA, Warburton EA, Baron JC (2013), “Diffusion and perfusion correlates of the 18F-MISO PET lesion in acute stroke: pilot study.” Eur J Nucl Med Mol Imaging Details

Carrera E, Jones PS, Morris RS, Alawneh J, Hong YT, Aigbirhio FI, Fryer TD, Carpenter TA, Warburton EA, Baron JC (2013), “Is neural activation within the rescued penumbra impeded by selective neuronal loss?” Brain 136(Pt 6):1816-29 Details

Ersche KD, Jones PS, Williams GB, Robbins TW, Bullmore ET (2013), “Cocaine dependence: a fast-track for brain ageing?” Mol Psychiatry 18(2):134-5 Details

Ersche KD, Jones PS, Williams GB, Smith DG, Bullmore ET, Robbins TW (2013), “Distinctive personality traits and neural correlates associated with stimulant drug use versus familial risk of stimulant dependence.” Biol Psychiatry 74(2):137-44 Details

Smith DG, Jones PS, Bullmore ET, Robbins TW, Ersche KD (2013), “Cognitive control dysfunction and abnormal frontal cortex activation in stimulant drug users and their biological siblings.” Transl Psychiatry 3:e257 Details

Smith DG, Jones PS, Williams GB, Bullmore ET, Robbins TW, Ersche KD (2013), “Overlapping decline in orbitofrontal gray matter volume related to cocaine use and body mass index.” Addict Biol Details

2012

Ersche KD, Jones PS, Williams GB, Turton AJ, Robbins TW, Bullmore ET (2012), “Abnormal brain structure implicated in stimulant drug addiction.” Science 335(6068):601-4 Details

Geva S, Baron JC, Jones PS, Price CJ, Warburton EA (2012), “A comparison of VLSM and VBM in a cohort of patients with post-stroke aphasia.” Neuroimage Clin 1(1):37-47 Details

Geva S, Jones PS, Crinion JT, Price CJ, Baron JC, Warburton EA (2012), “The effect of aging on the neural correlates of phonological word retrieval.” J Cogn Neurosci 24(11):2135-46 Details

Hughes JL, Jones PS, Beech JS, Wang D, Menon DK, Aigbirhio FI, Fryer TD, Baron JC (2012), “A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation.” Neuroimage 59(3):2007-16 Details

2011

Agarwal S, Jones PS, Alawneh JA, Antoun NM, Barry PJ, Carrera E, Cotter PE, O'Brien EW, Salih I, Scoffings DJ, Baron JC, Warburton EA (2011), “Does perfusion computed tomography facilitate clinical decision making for thrombolysis in unselected acute patients with suspected ischaemic stroke?” Cerebrovasc Dis 32(3):227-33 Details

Alawneh JA, Jones PS, Mikkelsen IK, Cho TH, Siemonsen S, Mouridsen K, Ribe L, Morris RS, Hjort N, Antoun N, Gillard JH, Fiehler J, Nighoghossian N, Warburton EA, Ostergaard L, Baron JC (2011), “Infarction of 'non-core-non-penumbral' tissue after stroke: multivariate modelling of clinical impact.” Brain 134(Pt 6):1765-76 Details

Carrera E, Jones PS, Alawneh JA, Klærke Mikkelsen I, Cho TH, Siemonsen S, Guadagno JV, Mouridsen K, Ribe L, Hjort N, Fryer TD, Carpenter TA, Aigbirhio FI, Fiehler J, Nighoghossian N, Warburton EA, Ostergaard L, Baron JC (2011), “Predicting infarction within the diffusion-weighted imaging lesion: does the mean transit time have added value?” Stroke 42(6):1602-7 Details

Carrera E, Jones PS, Iglesias S, Guadagno JV, Warburton EA, Fryer TD, Aigbirhio FI, Baron JC (2011), “The vascular mean transit time: a surrogate for the penumbra flow threshold?” J Cereb Blood Flow Metab 31(4):1027-35 Details

Ersche KD, Barnes A, Jones PS, Morein-Zamir S, Robbins TW, Bullmore ET (2011), “Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence.” Brain 134(Pt 7):2013-24 Details

Geva S, Jones PS, Crinion JT, Price CJ, Baron JC, Warburton EA (2011), “The neural correlates of inner speech defined by voxel-based lesion-symptom mapping.” Brain 134(Pt 10):3071-82 Details

Moustafa RR, Momjian-Mayor I, Jones PS, Morbelli S, Day DJ, Aigbirhio FI, Fryer TD, Warburton EA, Baron JC (2011), “Microembolism versus hemodynamic impairment in rosary-like deep watershed infarcts: a combined positron emission tomography and transcranial Doppler study.” Stroke 42(11):3138-43 Details

Takasawa M, Beech JS, Fryer TD, Jones PS, Ahmed T, Smith R, Aigbirhio FI, Baron JC (2011), “Single-subject statistical mapping of acute brain hypoxia in the rat following middle cerebral artery occlusion: a microPET study.” Exp Neurol 229(2):251-8 Details

2010

Calautti C, Jones PS, Guincestre JY, Naccarato M, Sharma N, Day DJ, Carpenter TA, Warburton EA, Baron JC (2010), “The neural substrates of impaired finger tapping regularity after stroke.” Neuroimage 50(1):1-6 Details

Calautti C, Jones PS, Naccarato M, Sharma N, Day DJ, Bullmore ET, Warburton EA, Baron JC (2010), “The relationship between motor deficit and primary motor cortex hemispheric activation balance after stroke: longitudinal fMRI study.” J Neurol Neurosurg Psychiatry 81(7):788-92 Details

Hughes JL, Beech JS, Jones PS, Wang D, Menon DK, Baron JC (2010), “Mapping selective neuronal loss and microglial activation in the salvaged neocortical penumbra in the rat.” Neuroimage 49(1):19-31 Details

Moustafa RR, Izquierdo-Garcia D, Jones PS, Graves MJ, Fryer TD, Gillard JH, Warburton EA, Baron JC (2010), “Watershed infarcts in transient ischemic attack/minor stroke with > or = 50% carotid stenosis: hemodynamic or embolic?” Stroke 41(7):1410-6 Details

2009

Donswijk ML, Jones PS, Guadagno JV, Carpenter TA, Moustafa RR, Fryer TD, Aigbirhio FI, Warburton EA, Baron JC (2009), “T2*-weighted MRI versus oxygen extraction fraction PET in acute stroke.” Cerebrovasc Dis 28(3):306-13 Details

Sharma N, Simmons LH, Jones PS, Day DJ, Carpenter TA, Pomeroy VM, Warburton EA, Baron JC (2009), “Motor imagery after subcortical stroke: a functional magnetic resonance imaging study.” Stroke 40(4):1315-24 Details

2008

Guadagno JV, Jones PS, Aigbirhio FI, Wang D, Fryer TD, Day DJ, Antoun N, Nimmo-Smith I, Warburton EA, Baron JC (2008), “Selective neuronal loss in rescued penumbra relates to initial hypoperfusion.” Brain 131(Pt 10):2666-78 Details

Sharma N, Jones PS, Carpenter TA, Baron JC (2008), “Mapping the involvement of BA 4a and 4p during Motor Imagery.” Neuroimage 41(1):92-9 Details

Takasawa M, Jones PS, Guadagno JV, Christensen S, Fryer TD, Harding S, Gillard JH, Williams GB, Aigbirhio FI, Warburton EA, Østergaard L, Baron JC (2008), “How reliable is perfusion MR in acute stroke? Validation and determination of the penumbra threshold against quantitative PET.” Stroke 39(3):870-7 Details

2007

Calautti C, Naccarato M, Jones PS, Sharma N, Day DD, Carpenter AT, Bullmore ET, Warburton EA, Baron JC (2007), “The relationship between motor deficit and hemisphere activation balance after stroke: A 3T fMRI study.” Neuroimage 34(1):322-31 Details

Takasawa M, Beech JS, Fryer TD, Hong YT, Hughes JL, Igase K, Jones PS, Smith R, Aigbirhio FI, Menon DK, Clark JC, Baron JC (2007), “Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18F-fluoromisonidazole and positron emission tomography: a pilot study.” J Cereb Blood Flow Metab 27(4):679-89 Details

2006

Calautti C, Jones PS, Persaud N, Guincestre JY, Naccarato M, Warburton EA, Baron JC (2006), “Quantification of index tapping regularity after stroke with tri-axial accelerometry.” Brain Res Bull 70(1):1-7 Details

Guadagno JV, Jones PS, Fryer TD, Barret O, Aigbirhio FI, Carpenter TA, Price CJ, Gillard JH, Warburton EA, Baron JC (2006), “Local relationships between restricted water diffusion and oxygen consumption in the ischemic human brain.” Stroke 37(7):1741-8 Details

Guadagno JV, Warburton EA, Jones PS, Day DJ, Aigbirhio FI, Fryer TD, Harding S, Price CJ, Green HA, Barret O, Gillard JH, Baron JC (2006), “How affected is oxygen metabolism in DWI lesions?: A combined acute stroke PET-MR study.” Neurology 67(5):824-9 Details

Naccarato M, Calautti C, Jones PS, Day DJ, Carpenter TA, Baron JC (2006), “Does healthy aging affect the hemispheric activation balance during paced index-to-thumb opposition task? An fMRI study.” Neuroimage 32(3):1250-6 Details

2005

Guadagno JV, Warburton EA, Jones PS, Fryer TD, Day DJ, Gillard JH, Carpenter TA, Aigbirhio FI, Price CJ, Baron JC (2005), “The diffusion-weighted lesion in acute stroke: heterogeneous patterns of flow/metabolism uncoupling as assessed by quantitative positron emission tomography.” Cerebrovasc Dis 19(4):239-46 Details