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Dr Laura Moreno-Lopez

Dr Laura Moreno-Lopez

Post-doctoral Research Associate


Biography:

Laura completed her PhD at the University of Granada (Spain) which focused in the application of brain imaging to the study of substance dependence. Her PhD included internships in the Division of Anaesthesia (University of Cambridge), Brookhaven National Laboratory (New York) and Department of Psychiatry (University of San Diego). After her PhD, she works in a project aimed to study the neural substrates of obesity. She joined the division of Anaesthesia of the University of Cambridge as a postdoctoral research in June 2013. She works now in the study of Neuroimaging biomarkers for risk and clinical outcome prediction of POD/POCD (Postoperative Delirium/Postoperative Cognitive Dysfunction) (Project BioCog).

Departments and Institutes

Clinical Neurosciences:

Research Interests

I am interested in the study of the neural basis of the cognitive, emotional and behavioural impairments associated with traumatic brain injury, substance addiction and obesity.

I am currently working in two projects aimed to study the neurobiological basis of depression following traumatic brain injury using a combination of structural and functional MRI and Neuroimaging biomarkers for risk and clinical outcome prediction of Postoperative cognitive dysfunction (BioCog)

Key Publications

Lauer J, Moreno-López L, Manktelow A, Carroll EL, Outtrim JG, Coles JP, Newcombe VF, Sahakian BJ, Menon DK, Stamatakis EA (2017). Neural correlates of visual memory in patients with diffuse axonal injury. Brain Injury, in press. 

Moreno-López L, Manktelow AE, Sahakian BJ, Menon DK, Stamatakis EA (2016). Anything goes? Regulation of the neural processes underlying response inhibition in TBI patients. Eur Neuropsychopharmacol7:159-69.

Moreno-López L, Contreras-Rodriguez O, Soriano-Mas C, Stamatakis EA, Verdejo-Garcia A (2016). Disrupted functional connectivity in adolescents obesity. Neuroimage Clin 12:262-8.

Moreno-López L, Sahakian BJ, Manktelow A, Menon DK, Stamatakis EA (2016). Depression following traumatic brain injury: A functional connectivity perspective. Brain Inj 30:1319-28.

Moreno-López L, Albein-Urios N, Martínez-González JM, Soriano-Mas C, Verdejo-García A (2016). Neural correlates of impaired self-awareness of apathy, disinhibition and dysexecutive deficits in cocaine-dependent individuals. Addict Biol, in press. doi: 10.1111/adb.12422. 

Moreno-López L, Albein-Urios N, Martinez-Gonzalez JM, Soriano-Mas C, Verdejo-García A (2014) Prefrontal Gray Matter and Motivation for Treatment in Cocaine-Dependent Individuals with and without Personality Disorders. Front Psychiatry 5:52 

Moreno-López L, Perales JC, van Son D, Albein-Urios N, Soriano-Mas C, Martinez-Gonzalez JM, Wiers RW, Verdejo-García A (2014) Cocaine use severity and cerebellar gray matter are associated with reversal learning deficits in cocaine-dependent individuals. Addict Biol 20:546-56.

Albein-Urios N, Martinez-Gonzalez JM, Lozano Ó, Moreno-López L, Soriano-Mas C, Verdejo-Garcia A (2013) Negative urgency, disinhibition and reduced temporal pole gray matter characterize the comorbidity of cocaine dependence and personality disorders. Drug Alcohol Depend 132:231-7.

Moreno-López L, Fernández-Serrano MJ, Stamatakis EA, Gómez-Río M, Rodríguez-Fernández A, Pérez-García M, Verdejo-García A (2013) [Differential association between the regional metabolism of the prefrontal cortex and limbic structures, and the time of abstinence in substance dependent individuals]. Adicciones 25:348-55

Caracuel A, Verdejo-García A, Fernández-Serrano MJ, Moreno-López L, Santago-Ramajo S, Salinas-Sánchez I, Pérez-García M (2012) Preliminary validation of the Spanish version of the Frontal Systems Behavior Scale (FrSBe) using Rasch analysis. Brain Inj 26:844-52.

Fernández-Serrano MJ, Cesar Peraleslópez J, Moreno-López L, Santos-Ruiz A, Pérez-García M, Verdejogarcía A (2012) [Impulsivity and compulsivity in cocaine dependent individuals]. Adicciones 24:105-13.

Fernández-Serrano MJ, Perales JC, Moreno-López L, Pérez-García M, Verdejo-García A (2012) Neuropsychological profiling of impulsivity and compulsivity in cocaine dependent individuals. Psychopharmacology (Berl) 219:673-83.

Moreno-López L, Catena A, Fernández-Serrano MJ, Delgado-Rico E, Stamatakis EA, Pérez-García M, Verdejo-García A (2012) Trait impulsivity and prefrontal gray matter reductions in cocaine dependent individuals. Drug Alcohol Depend 125:208-14.

Moreno-López L, Soriano-Mas C, Delgado-Rico E, Rio-Valle JS, Verdejo-García A (2012) Brain structural correlates of reward sensitivity and impulsivity in adolescents with normal and excess weight. PLoS One 7:e49185.

Moreno-López L, Stamatakis EA, Fernández-Serrano MJ, Gómez-Río M, Rodríguez-Fernández A, Pérez-García M, Verdejo-García A (2012) Neural correlates of hot and cold executive functions in polysubstance addiction: association between neuropsychological performance and resting brain metabolism as measured by positron emission tomography. Psychiatry Res 203:214-21.

Moreno-López L, Stamatakis EA, Fernández-Serrano MJ, Gómez-Río M, Rodríguez-Fernández A, Pérez-García M, Verdejo-García A (2012) Neural correlates of the severity of cocaine, heroin, alcohol, MDMA and cannabis use in polysubstance abusers: a resting-PET brain metabolism study. PLoS One 7:e39830.

Fernández-Serrano MJ, Moreno-López L, Pérez-García M, Viedma-Del Jesús MI, Sánchez-Barrera MB, Verdejo-García A (2011) Negative mood induction normalizes decision making in male cocaine dependent individuals. Psychopharmacology (Berl) 217:331-9.