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Dr Claire O'Callaghan

Dr Claire O'Callaghan

Visiting research fellow

NHMRC Neil Hamilton Fairley Early Career Fellow


Office Phone: (3)30272

Biography:

I am a clinical research fellow with a focus on neuropsychiatric symptoms in neurodegenerative conditions. Symptoms such as apathy, depression, impulsivity and social impairments are common in neurodegenerative disease. My research takes a transdiagnostic approach across different conditions, including Parkinson’s disease, Huntington’s disease and frontotemporal dementia, to study neuropsychiatric symptoms. Drawing from both clinical and cognitive neurosciences, I aim to develop novel neuropsychological assessment tools to detect these symptoms, in combination with multimodal neuroimaging and pharmacological manipulations. Together, my goal is to refine our characterisation of these symptoms and better establish their neural basis, to ultimately improve therapeutic strategies.

Departments and Institutes

Psychology:

Keywords

  • Frontotemporal dementia
  • cognitive
  • neuroimaging
  • behaviour
  • dementia
  • Parkinson's disease

Key Publications

O’Callaghan C, Bertoux M, Irish M, Shine JM, Wong S, Spiliopoulos L, Hodges JR & Hornberger M. (2016). Fair play – Social norm compliance failures in behavioural variant frontotemporal dementia, Brain, 139(1), 204-216

O’Callaghan C, Hornberger M, Balsters JH, Halliday GM, Lewis SJG & Shine JM (2016). Cerebellar atrophy in Parkinson’s disease and its implication for network connectivity, Brain, 139(3), 845-855

O'Callaghan C, Shine JM, Lewis, SJG, Andrews-Hanna, JR & Irish M. (2015) Shaped by our thoughts – A new task to assess spontaneous cognition and its associated neural correlates in the default network, Brain and Cognition, 93(0):1-10.

O'Callaghan C, Bertoux M & Hornberger M. (2014) Beyond and below the cortex: The contribution of striatal dysfunction to cognition and behaviour in neurodegeneration. Journal of Neurology, Neurosurgery and Psychiatry, 85, 371-378.

O'Callaghan C, Naismith SL, Hodges, JR, Lewis SJG & Hornberger M. (2013) Fronto-striatal atrophy correlates of inhibitory dysfunction in Parkinson’s disease versus behavioural variant frontotemporal dementia. Cortex, 49(7), 1833-43.